Postoperative recurrence in hepatocellular carcinoma: Comparison between percutaneous ethanol injection and radiofrequency ablation.

نویسندگان

  • Kaoru Iwata
  • Tetsuro Sohda
  • Shinya Nishizawa
  • Hidetoshi Nakane
  • Makoto Yoshikane
  • Yasuhiro Koyama
  • Daisuke Morihara
  • Yasuaki Takeyama
  • Yuko Uehara
  • Yuji Kitamura
  • Makoto Irie
  • Satoshi Syakadou
  • Masanori Yokoyama
  • Seiichiro Kamimura
  • Hiroshi Watanabe
  • Shotaro Sakisaka
چکیده

AIM Recently percutaneous ethanol injection (PEI) turned into percutaneous radiofrequency ablation (PRFA), and it has become widely used for the treatment of hepatocellular carcinoma (HCC). The present study was to compare the incidence in postoperative HCC recurrence between these two therapeutic approaches. METHODS One hundred and sixty-eight first-time HCC in patient cases were chosen for PEI (n=94) and PRFA (n=74). The localized recurrence rate based on the operator's experience in percutaneous treatment for HCC (on <5 years versus >/=5 years experience) was examined. RESULTS The PRFA group demonstrated a significantly lower localized recurrence rate within 2 years than the PEI group (8% and 22%, respectively, P<0.01). The local recurrence rate of HCC within 2 years after PEI was significantly lower in those for whom the operator's experience was more than 5 years compared to those for whom it was less than 5 years (12% versus 24%, respectively, P<0.05). In contrast, after PRFA there was no significant difference between these two groups of <5 years and of >/=5 years experience (8% versus 8%, respectively, P=0.98). CONCLUSION The present study demonstrated that PRFA resulted in a lower rate of local recurrence in comparison to conventional PEI, regardless of the operator's experience.

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Percutaneous radiofrequency ablation of hepatocellular carcinoma compared to percutaneous ethanol injection in treatment of cirrhotic patients: an Italian randomized controlled trial.

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REFERENCES 1. Kosugi C, Furuse J, Ishii H, et al. Needle tract implantation of hepatocellular carcinoma and pancreatic carcinoma after ultrasound-guided percutaneous puncture: clinical and pathologic characteristics and the treatment of needle tract implantation. World J Surg 2004; 28: 29-32. 2. Ishii H, Okada S, Nose H, et al. Local recurrence of hepatocellular carcinoma after percutaneous eth...

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Thoracoscopic ethanol injection and radiofrequency ablation for the treatment of hepatocellular carcinoma located immediately under the diaphragm.

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عنوان ژورنال:
  • Hepatology research : the official journal of the Japan Society of Hepatology

دوره 36 2  شماره 

صفحات  -

تاریخ انتشار 2006